Opioid medications interact with opioid receptors in the body, reducing pain and altering the effects of certain chemicals in the brain. Their effect may involve suppressing the pain perception center in the brain or blocking the transmission of pain signals by nerves. Opioids are used in the treatment of severe pain, such as that resulting from surgical procedures, trauma, or cancer. They are available only with a prescription, meaning you cannot purchase them without one or before completing the prescribed dosage. These medications, which can be used recreationally, carry a high risk of addiction in such cases.

Various drugs, including morphine, oxycodone, hydrocodone, and fentanyl, fall into this category.

Common side effects of opioid medications, although varying from person to person, include:

• Drowsiness, dizziness, and lightheadedness
• Nausea and vomiting
• Itching
• Constipation
• Respiratory depression: In high doses or if misused, opioids can slow down respiratory rate, affecting the brain's respiratory center and potentially leading to death.
• Addiction: Prolonged use or misuse of opioids can lead to physical and psychological dependence.